Active ingredient
Pantoprazole, usually in salt form Pantoprazole sodium
Explanation/Definition
Pantozol® belongs to the group of proton pump inhibitors and reduces the formation of stomach acid. It is used for the treatment of diseases in which increased stomach acid production irritates the sensitive or already damaged mucous membranes of the esophagus (esophagus), stomach (gaster) and duodenum.
Dosage forms
Pantozol® is available in 20mg and 40mg dosages. Normally it is taken in the form of enteric coated tablets. However, it can also be purchased as a 40mg dry substance for making an infusion (‘drip’) directly into the vein. Pantozol® belongs to the group of prescription drugs.
Mode of action
The parietal cells of the stomach produce about 2 liters of gastric juice per day. The hydrochloric acid (HCl) contained in it splits the protein taken in with food, kills bacteria and prepares further steps of digestion. In simple terms, one can imagine that the gastric acid is produced by a pump.
This pump is located in the cells of the stomach lining and pumps hydrochloric acid into the stomach opening, e.g. stimulated by digestive hormones. The active ingredient Pantoprazole binds irreversibly to the proton pumps and thus blocks hydrochloric acid production by up to 90%. Only when the body has produced new proton pumps can the gastric juice be secreted normally again. With a single administration not all proton pumps are blocked! If Pantozol® is taken daily, the maximum effect is therefore achieved after 2-3 days.
Dosage and application
The dosage and duration of treatment depends on the area of application. Here the treating physician decides, depending on the existing clinical picture. Pantozol® is taken unchewed with some liquid.
To achieve optimum efficacy, the drug should be taken about half an hour before meals. Pantozol® with an effective strength of 20mg is frequently used in the prevention of disease patterns. These include: In addition, Pantozol® 20mg can be used for symptomatic treatment, i.e. purely aimed at the symptoms.
These include: Complaints caused by the reflux of gastric acid into the esophagus Complaints caused by acidic belching Pantozol® with an effective strength of 40 mg is, however, more suitable for acute clinical pictures. These include: Acute inflammation of the oesophagus (esophagitis) due to reflux of stomach acid Stomach ulcers and duodenal ulcers Zollinger-Ellison syndrome Infection with the bacterium Helicobacter pylori, in the presence of stomach and duodenal ulcers Simultaneous administration of antibiotics to kill the bacterium and heal the ulcers (‘Helicobacter pylori eradication’)
- Recurrence (relapse) of an inflammation of the esophagus caused by reflux of gastric acid (reflux esophagitis)
- Recurrence of ulcers in the stomach or duodenum, caused by the increased intake of certain pain or rheumatic drugs
- Discomfort caused by the reflux of gastric acid into the esophagus
- Complaints caused by acid burping
- Acute inflammation of the esophagus (esophagitis) due to reflux of gastric acid
- Stomach ulcers and duodenal ulcers (ulcer)
- Zollinger-Ellison Syndrome
- Infection with the bacterium Helicobacter pylori, in the presence of gastric and duodenal ulcers. Simultaneous administration of antibiotics to kill the bacterium and heal the ulcers (‘Helicobacter pylori eradication’)
