Laboratory parameters of the 1st order – obligatory laboratory tests.
- Direct pathogen detection from blood or urine, stool, bone marrow, duodenal secretions, or
- Antibody detection [in acute illness, pathogen detection (e.g., from stool) is the investigation of choice], can be determined:
- S. paratyphi B-Ak (OH antigens).
- S. typhimurium-Ak (OH antigens).
- S. typhi-Ak (O antigen).
- S. typhi-Ak (H antigen)
- S. enteritidis-Ak (OH antigens).
Direct or indirect detection of Salmonella parathyphi must be reported by name, if the evidence indicates acute infection (Act on the Prevention and Control of Infectious Diseases in Humans).
2nd order laboratory parameters – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification.
- Small blood count
- Differential blood count
- Inflammatory parameters – ESR (erythrocyte sedimentation rate) or CRP (C-reactive protein) or PCT (procalcitonin).
- Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, ketone, urobilinogen, bilirubin, blood), sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing of suitable antibiotics for sensitivity / resistance).
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Coagulation parameters – PTT, Quick
