Penile Cancer

In penile carcinoma – colloquially called penile cancer – (synonyms: Malignant neoplasm of the glans penis; Malignant neoplasm of the penile skin; Malignant neoplasm of the prepuce; Malignant neoplasm of the corpus cavernosum penis; Malignant neoplasm of the penis; Malignant neoplasm of the penile shaft; Malignant neoplasm of the prepuce; Carcinoma of the glans penis; Carcinoma of the corpus cavernosum of the penis; cancer of the glans penis; cancer of the corpus cavernosum of the penis; malignant melanoma of the prepuce; malignant melanoma of the penis; malignant melanoma of the prepuce; nonmelanoma malignant neoplasm of the skin of the prepuce; nonmelanoma malignant neoplasm of the skin of the penis a. n.k.; nonmelanoma malignant neoplasm of the skin of the prepuce; carcinoma of the prepuce; cancer of the prepuce ICD-10 C60.-: Malignant neoplasm of the penis) is a malignant neoplasm (malignant neoplasm) of the penis.

Penile carcinoma is squamous cell carcinoma (PEK) in approximately 95% of cases. It often originates from the epithelium of the glans penis (glans) or the inner preputial leaf (foreskin leaf). For histologic forms of penile carcinoma, see Classification.

Peak incidence: Approximately 60% of affected individuals are older than 60 years: the majority (approximately 60%) of affected men are ≥ 70 years of age. Note: Approximately 40% of affected individuals are < 60 years of age.

The incidence (frequency of new cases) is 0.5-1.7-2 cases per 100,000 men per year (in North America and Europe). In developing countries of Africa and Latin America, the incidence is as high as 9 cases per 100,000 men.

Course and prognosis: Initially, uncharacteristic skin changes occur (red or white spot; nodular changes; possibly also contact bleeding or bleeding tendency) in the area of the glans penis (glans) or the inner preputial leaf (foreskin leaf). Only later does an exophytic or, more rarely, an ulcerative tumor become apparent. Unfortunately, the diagnosis of penile carcinoma is usually made at an advanced stage.In advanced stages, a lymph node enlargement in the groin area is palpable. Confirmation of diagnosis by biopsy (tissue sampling). Surgical measures depend on the tumor stage.Most recurrences occur within the first 2 years. The chances of cure (70-90%) are better the earlier the tumor is detected. If diagnosed early, penile carcinoma can be cured in >90% of cases.The 5-year survival rate for distant metastases is circa 5%.