Pentamidine

Products

Pentamidine is commercially available as a dry substance for injection or inhalation (pentacarinate). It has been approved in many countries since 1990.

Structure and properties

Pentamidine (C₁₉H₂₄N₄O₂, M_r = 340.4 g/mol) is an aromatic diamidine. It exists as a pentamidine diisetionate, a white powder or colorless crystals that are readily soluble in water.

Effects

Pentamidine (ATC P01CX01) has antiparasitic properties against various parasites, including .

Indications

• Therapy and secondary prophylaxis of Pneumocystis pneumonia when cotrimoxazole is contraindicated.
• Trypanosomiasis