Peritonitis: Drug Therapy

Therapeutic target

  • Elimination of the pathogens
  • Avoidance of complications

Therapy recommendations

  • Antibiosis (antibiotic therapy) for:
    • Secondary peritonitis (e.g., perforation/rupture of an abdominal organ): choice of antibiotics depending on the presence of focal (“focal”) or diffuse peritonitis (inflammation throughout the abdomen).
    • spontaneous-bacterialPeritonitis (SBP; special form of primary peritonitis, which occurs in the context of a therapy-refractory ascites (abdominal dropsy that does not respond to treatment)); means of choice for secondary prophylaxis (measure to prevent further progression of a disease that has already occurred) are gyrase inhibitors (permanent) in liver cirrhosis (“shrunken liver”; end stage of chronic liver disease).