Pertussis (Whooping Cough): Symptoms, Complaints, Signs

The following symptoms and complaints may indicate pertussis (whooping cough):

Symptoms in the catarrhal stage (initial stage with a cold-like cough; usually lasts 1-2 weeks).

  • Cough
  • Common cold
  • General weakness in performance
  • Mild fever (rather rare)

Symptoms in the convulsivum stage (bouts of coughing (staccato cough); usually lasts 4-6 weeks).

  • Coughing fits that occur intermittently, clustered at night; are often accompanied by regurgitation of mucus
  • May also occur simply as a prolonged cough

Symptoms of stage decrementi (about 6-10 weeks).

  • Gradual subsiding of the symptoms of stage convulsivum.

Other indications

  • Any persistent cough (no resolution after 7-14 days), which often occurs in attacks and at night, should be thought of pertussis!
  • After the coughing attacks may be inspiratory stridor (breathing sound when inhaling) or vomiting.
  • Apneas (cessations of breathing) may occur in infants.
  • In adulthood often shows an atypical mild course with nonspecific dry cough. In the stage catarrhale, the distinction from a cold is often difficult. After one to two weeks (stage convulsivum), the typical attack-like barking cough occurs, which can last four weeks or longer.

Diagnosis-leading symptoms in pertussis (whooping cough) in children and adults; recommendations of the CHEST Guideline and Expert Panel Report.

Children Adults
Age group 0-18 years; vomiting after cough attack:sensitivity 60.0%; specificity 66%. Cough attacks and absence of fever:sensitivity (93.2% and 81.8%, respectively); specificity (20.6% and 18.8%, respectively)
Recommendations Recommendations
  • Three typical features should be assessed in children with acute cough (<4 weeks): Coughing spells, vomiting after coughing, and inspiratory stridor (consensus without grade of recommendation).
  • Vomiting after coughing attacks should be thought of as a possible cause of pertussis (recommendation grade 2C)
  • When coughing attacks or inspiratory whistling occur, pertussis should be thought of as a possible cause (consensus without grade of recommendation)
  • In adults with acute (<3 weeks) or subacute cough (3-8 weeks), four key features should be assessed to include or exclude pertussis: Cough attacks, vomiting after cough attacks, inspiratory stridor, and absence of fever (recommendation grade 2C).
  • If there is inspiratory whistling or vomiting after the coughing attack, the diagnosis of pertussis should be considered likely (Grade of Recommendation 2C)
  • If the patient has a fever or the cough is not seizure-like, Bordetella pertussis infection is unlikely (Grade of Recommendation 2C).