In many cases, the infection is asymptomatic, but the following symptoms and complaints may indicate infectious mononucleosis (glandular fever):
- Enanthem – rash in the area of the mucous membranes.
- Morbilliform exanthema (rash) that occurs mainly on the arms and trunk of the body; usually papular.
- Angina (sore throat)
- Fever
- Foetor ex ore (bad breath)
- Hepatitis (inflammation of the liver)
- Lymphadenopathy (lymph node enlargement): posterior cervical lymph nodes (specificity 0.87; LR 3.1) and axillary or inguinal lymph nodes (specificity 0.82-0.91; LR 3.0-3.1).
- Meningitis (meningitis) – very rare.
- Fatigue
- Myalgia (muscle pain)
- Neuritis (inflammation of the nerves)
- Petechiae (flea-like hemorrhages) on the palate (specificity 0.95; positive likelihood ratio, LR 5.3)
- Pneumonia (pneumonia)
- Dysphagia (difficulty swallowing)
- Splenomegaly (splenomegaly) (frequency: 7-53%, (specificity 0.71-0.99; LR 1.9-6.6), possibly also hepatomegaly (liver enlargement).
