Pfeiffer’s Glandular Fever (Infectious Mononucleosis): Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests.

  • EBV rapid test for the detection of antibodies.
  • Serological tests such as the EBV IgM/IgG ELISA and EA (early antigen).
  • Small blood count [total leukocyte count is usually only mildly to moderately elevated]
  • Differential blood count [relative lymphocytosis (total number of lymphocytes in the blood increased) or increased atypical and immature lymphocytes (belong to the white blood cells) and monocytosis (increase in the number of monocytes)]
  • Lactate dehydrogenase (LDH) [obligatory elevated]

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • EBV immunoblot – In diagnostic problem cases.
  • HIV test – In mononucleosis-like clinical picture.