The following are the most important diseases or complications that may be contributed to by pharyngitis (pharyngitis):
Respiratory system (J00-J99)
- Laryngeal edema – accumulation of water in the larynx.
- Mediastinitis – inflammation of the connective tissue of the mediastinal cavity.
- Peritonsillar abscess (PTA) – spread of inflammation to the connective tissue between tonsil (tonsils) and M. constrictor pharyngis with subsequent abscessation (accumulation of pus); predictors of peritonsillar abscess: male sex (1 point); age 21-40 years and smoker; clinical findings: unilateral sore throat/severe pain (3 points), trismus (lockjaw; 2 points), lumpy voice (1 point), and uvular/palatal deviations (1 point). Interpretation: threshold at which the probability of the presence of PTA increases significantly is a total score of 4. Note: test achieved near-maximal negative predictive value and high sensitivity (percentage of diseased patients in whom the disease is detected by use of the test, i.e., a positive test result occurs), but relatively low specificity (probability that actually healthy individuals who do not have the disease in question are also detected as healthy in the test).
- Pharynxphlegmon – rapidly progressive inflammation of the tissues surrounding the tonsils, originating from the tonsils.
- Sinusitis (sinus infection).
Skin and subcutaneous (L00-L99)
- Pustulosis palmares et plantares – pustules on the palms of the hands and soles of the feet.
Cardiovascular system (I00-I99)
- Acute rheumatic fever (ARF) – specific reaction occurring after infection with serogroup A streptococci, leading to arthritides (inflammation of joints), inflammation of the heart such as pericarditis and endocarditis (inflammation of the pericardium and pericardium), and CNS involvement in the form of chorea minor; used to be quite common in children before the start of antibiotic therapy
- Endocarditis – inflammation of the inner lining of the heart, usually the heart valves are affected.
- Myocarditis (inflammation of the heart muscle)
- Pericarditis (inflammation of the pericardium)
- Thrombangiitis obliterans (synonyms: endarteritis obliterans, Winiwarter-Buerger disease, Von Winiwarter-Buerger disease, thrombangitis obliterans) – vasculitis (vascular disease) associated with recurrent (recurring) arterial and venous thrombosis (blood clot (thrombus) in a blood vessel); symptoms: Exercise-induced pain, acrocyanosis (blue discoloration of the body appendages), and trophic disturbances (necrosis/tissue damage resulting from the death of cells and gangrene of the fingers and toes in advanced stages).
- Vasculitis (vascular inflammation).
Infectious and parasitic diseases (A00-B99).
- Sepsis (blood poisoning)
Ears – mastoid process (H60-H95)
- Otitis media (inflammation of the middle ear)
Symptoms and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).
- Dyspnea (shortness of breath)
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).
- Acute poststreptococcal glomerulonephritis (APSGN; kidney disease, with inflammation of the renal filterlets (glomeruli)).
