Phenoxybenzamine

Products

Phenoxybenzamine is commercially available in the form of capsules (Dibenzyran). The drug is not registered in many countries.

Structure and properties

Phenoxybenzamine (C18H22ClNO, Mr = 303.8 g/mol) is a haloalkylamine.

Effects

Phenoxybenzamine (ATC C04AX02) is an irreversible alpha blocker that inactivates alpha receptors by alkylation. It blocks norepinephrine actions, is vasodilatory, and lowers blood pressure.

Indications

Phenoxybenzamine is used to treat bladder voiding dysfunction and pheochromocytoma.