Products
There are no drugs containing physostigmine on the market in many countries.
Structure and properties
Physostigmine (C15H21N3O2, Mr = 275.3 g/mol)
Stem
Fabaceae.
Effects
Physostigmine is indirectly parasympathomimetic by inhibiting acetylcholinesterase; see under cholinesterase inhibitors.
Indications
- Alzheimer’s disease
- As a miotic
- Antidote to curare poisoning and parasympatholytics, e.g., atropine.