Postthrombotic Syndrome: Symptoms, Causes, Treatment

Postthrombotic syndrome (PTS) (ICD-10 I87.0) is a possible late complication after the occurrence of deep vein thrombosis (DVT).

Postthrombotic syndrome is seen after approximately 10-15 years, in 40-60% of conventionally treated patients with deep vein thrombosis (DVT). Peak incidence: the maximum incidence of post-thrombotic syndrome is between 40 and 50 years of age in women and between 70 and 80 years of age in men. After age 70, the incidence for postthrombotic syndrome increases threefold. The prevalence (disease incidence) is approximately 2-5% of the population in western industrialized countries. Course and prognosis: Postthrombotic syndrome is usually a chronic condition with various late sequelae, the severity of which depends on the extent of the thrombosis and the formation of a functional collateral circulation. Timely and optimal compression therapy can slow the progression of the pathological process.