Pregnancy and lactation
Thomapyrin® should not be taken during the first 6 months of pregnancy. The inhibition of cyclooxygenase by ASA and the resulting lack of prostaglandins can lead to errors in the development of the child. If it is necessary to take Thomapyrin®, the lowest possible doses should be used.
Thomapyrin® must never be taken during the third stage of pregnancy. ASA induces prostaglandin deficiency, which leads to cardiopulmonary abnormalities, such as premature closure of the ductus totalli, as well as renal failure. Furthermore, the risk of bleeding in the mother and embryo is greatly increased.
In the last stage, Thomapyrin® can inhibit labor and thus delay delivery. If taken over a longer period of time, the risk of miscarriage increases due to the caffeine it contains. Since the ingredients of Thomapyrin® (ASA, paracetamol and caffeine) are transmitted via breast milk, they should not be taken during breastfeeding.
Short-term intake is not a problem; for longer periods, breastfeeding should be stopped. The caffeine can have negative effects on the infant’s condition.
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