Psoriasis: Prevention

To prevent psoriasis (psoriasis), attention must be paid to reducing individual risk factors.

Behavioral risk factors

• Diet
  • High intake of the omega-6 fatty acid arachidonic acid (animal foods, especially pork and pork products and tuna).
  • Weight gain
• Consumption of stimulants
  • Alcohol
  • Tobacco (smoking), including passive smoking for children.
• Psycho-social situation
  • Psychological stress
• Chemical skin irritation
• Mechanical skin irritation
• Thermal skin irritation such as sunburn
• Excess weight (BMI ≥ 25; obesity)

Prevention factors (protective factors)

• Genetic factors:
  • Genetic risk reduction depending on gene polymorphisms:
    • Genes/SNPs (single nucleotide polymorphism):
      • Gene: IL23R (encodes a cytokine receptor on a subpopulation (subset) of effector T cells).
      • SNP: rs11209026 in the gene IL23R
        • Allele constellation: AG (0.6-fold).
        • Allele constellation: AA (< 0.6-fold)