Interactions of pyridoxine (vitamin B6) with other micronutrients (vital substances):
Vitamin B12, vitamin B6, and folic acid
The metabolism of homocysteine, which plays a mediating role in the metabolism of sulfur-containing amino acids, provides an example of the interdependence of vital substances to optimize or maintain physiological functions and thus health. Healthy individuals can metabolize homocysteine in the following two ways:
- Synthesis of methionine from homocysteine with the help of a folate coenzyme and a vitamin B12-dependent enzyme.
- Conversion of homocysteine to another amino acid – cysteine – with the help of a vitamin B6-dependent enzyme.
Consequently, the amount of homocysteine in the blood is regulated by three vitamins: Folic acid, vitamin B12 and vitamin B6.
