Rejection reaction after stem cell transplantation | Rejection reaction

Rejection reaction after stem cell transplantation

The most common complications after stem cell transplantation include infections caused by the immunosuppressive drugs and so-called graft-versus-host disease, in which immune cells of the donor are directed against the cells of the recipient. There is an increased risk, especially in the first year, especially in the first six months after the procedure. In contrast, a rejection reaction in the usual sense is rarely observed.

It is accompanied by a lack of growth of the transplanted cells and a reduced cell count in the blood. In addition, unspecific fever is frequently observed. Immunosuppressive drugs are used in prophylactic and therapeutic applications. If this treatment is not sufficient, a new transplantation may be sought.