Although radiographic signs of renal osteopathy are detectable in nearly half of affected individuals, symptoms occur in only up to 10%. These include:
Leading symptoms
- Bone pain
- Muscle weakness, occurring mainly in the proximal (trunk) muscles
- Spontaneous fractures – spontaneous bone fractures.
Further notes
- In children, there are growth disturbances similar to rickets (short stature) and bending of the extremities (renal rickets).
- In adults, there is a mixture of osteomalacia (bone softening), osteodystrophy and osteosclerosis (sclerosis (hardening) of bone tissue).