Pathogenesis (development of disease
Ablatio retinae (retinal detachment) can occur due to a hole in the retina (retina), proliferative retinopathy (retinal disease, or it can be caused by tumors.
Etiology (causes)
Biographic causes
- Genetic burden from parents, grandparents.
Disease-related causes of secondary retinal detachment.
Eyes and eye appendages (H00-H59).
- Degenerative changes of the retina (retinal) (most common cause of tear-related ablation).
- Myopia (nearsightedness)
- Up to -3 diopters (D): 4x
- > -3 D: 10-fold
- Retinopathy (retinal disease).
Neoplasms – tumor diseases (C00-D48)
- Tumors of the eye, unspecified; e.g., uveal melanoma (uveal melanoma; may lead to concomitant retinal detachment; risk factors: fair-skinned people and patients with dysplastic nevus syndrome; people aged 60-70 years are particularly at risk)
Pregnancy, childbirth and puerperium (O00-O99).
- Gestational hypertension (high blood pressure in pregnancy)/pre-eclampsia (2.2-fold).
Injuries, poisoning, and other sequelae of external causes (S00-T98).
- Eye injuries, unspecified
Operations
- Cataract surgery (cataract surgery) – six years after surgery, the risk of ablation increases by a factor of 7 and continues to increase with increasing postoperative duration
Medication
- Quinolones/fluoroquinolones/gyrase inhibitors (ciprofloxacin, moxifloxacin, nalidixic acid, norfloxacin, lomefloxacin, levofloxacin, ofloxacin).