The following are the most important diseases or complications that may be contributed to by rickets or osteomalacia:
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Hypocalcemia (calcium deficiency) → tetany (disturbance of motor function and sensitivity due to hyperexcitability of nerves and muscles).
Musculoskeletal system and connective tissue (M00-M99).
- Skeletal changes due to decreased mineralization of the osteoid (due to calcium deficiency or phosphate deficiency).
- O-legs due to coxa vara, genu varum.
Nervous system (G00-G99)
- Muscle weakness due tolack of vitamin D at the vitamin D receptors of muscle cells.
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Chronic pain
Injuries, poisonings, and other consequences of external causes (S00-T98)
- Increased occurrence of fractures (bone fractures) due to decreased mineralization of the osteoid (due to calcium deficiency or phosphate deficiency) = insufficiency fractures (typical of osteomalacia); typical localizations:
- Os sacrum (sacrum)
- Pelvis
- Tibial plateau (plateau of the tibia).
- Ossa metatarsalia (metatarsal bone)