2nd order laboratory parameters – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification
- Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
- Parotitis epidemica: see under the disease of the same name.
- Cytomegaly: see under the disease of the same name.
- HIV infection: see under the disease of the same name.
- Lues serology – for suspected syphilis (lues; venereal disease).
- Rheumatism diagnostics – CRP (C-reactive protein) or BSG (blood sedimentation rate); rheumatoid factor (RF), CCP-AK (cyclic citrulline peptide antibodies), ANA (antinuclear antibodies); HLA-B27 – on suspicion of Sjögren’s or Sicca syndrome.
- Detection of auto-antibodies (IgG) against antigens in the cytoplasm of the salivary duct epithelium (biopsy material / tissue sampling material) – if Sjögren’s or Sicca syndrome is suspected.
- Tuberculin skin test – in this procedure, purified tuberculin is injected into the skin; the test cannot distinguish between old and fresh infection [false-positive results occur in patients who have previously received BCG vaccination or otherwise come into contact with mycobacteria; in Heerfordt syndrome: negative].
- Fine needle aspiration biopsy (FNAB) for histology (tissue sampling for fine tissue examination) – if Heerfordt syndrome, Küttner tumor is suspected.
