Laboratory parameters of the 1st order – obligatory laboratory tests.
- Examination of the sample obtained from the physical examination (skin scales, from the area of the ducts or in the immediate vicinity) under the microscope, if necessary also dermoscopy (reflected light microscopy) [detection: mites, feces and / or eggs].
- Screening for other sexually transmitted diseases (STD, sexually transmitted disease).
Laboratory parameters 2nd order – depending on the results of the history, physical examination and mandatory laboratory parameters – for differential diagnostic clarification.
- Vesicles (vesicles)/pustules (pustules); collection of fluid for further diagnosis:
- Native (potassium hydroxide) to exclude mycoses (fungi).
- Gram/Giemsa stain (bacteria, analysis of inflammatory cells: neutrophils and eosinophils granulocytes/belong to the leukocyte (white blood cell) group).
- PCR diagnostics (polymerase chain reaction): v. a. HSV-1-PCR/HSV-2-PCR (nucleic acid amplification technique (NAT)) – direct detection of viral DNA with PCR from efflorescences.
- Skin biopsy (tissue removal from the skin) for histological (fine tissue)/immunohistochemical examination (including to exclude histiocytosis/Langerhans cell histiocytosis (LCH)).