Severe Acute Respiratory Syndrome (SARS): Causes

Pathogenesis (disease development)

The disease is caused by the Sars-CoV-1 coronavirus (SARS-associated coronavirus, SARS-CoV). The virus belongs to the coronavirus family (Coronaviridae).

The natural reservoir of the pathogen is probably flying foxes (bats).

Infection with the SARS virus leads to acute severe lung injury characterized by increased permeability (permeability) of the pulmonary capillaries and rapidly increasing pulmonary edema.

Etiology (Causes)

Biographic Causes

  • Age – older age and residence in health care facilities are risk factors.
  • Occupation – medical personnel

Disease-related causes

Infectious and parasitic diseases (A00-B99).

  • SARS coronavirus infection (SARS-associated coronavirus, SARS-CoV).