2nd order laboratory parameters – depending on the results of the medical history, physical examination, etc. – for differential diagnostic clarification
- Small blood count
- Differential blood count
- Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
- Allergy tests
- Environmental analysis
- Central substances are lindane and pentachlorophenol (PCP). PCP is a substance that is not only used as a wood preservative. Since 1991, PCP has been banned from manufacture, but not from use. Therefore, depending on the type of manufacture and country, PCP is in emulsion paints, rubber mattresses, hygiene products, adhesives, cooling water systems, glues, sanitary and industrial cleaners, hoses, shoe linings, boots, stockings and tents.
- PCP is absorbed via inhalation or through the skin. The highest concentrations can be detected in the liver and kidney. The substances are also detectable in endocrine glands. In some cases, contamination of foodstuffs occurs via the outer packaging, which contains PCP. Under the influence of formaldehyde, PCP can have a 5-fold increased effect. For the analytics is aggravating that in all people a certain basic load is now detectable in blood and urine.
- Particularly high levels can be detected after periods of fasting by dissolving the PCP’s from the fat depots of the patient. Increased intake of dioxins leads to a reduction in PCP levels, but at the same time may feign a lower burden on the organism than is actually given.
- PCB (polychlorinated biphenyls) is a group of substances under which 209 individual substances are hidden. They have a low volatility and water solubility, but dissolve well in fats, oils or organic solvents. PCBs can be found in paints, flame retardants, permanently elastic joint compounds, adhesives, lamp capacitors, lubricants, plasticizers and transformers. PCB’s can also be detected in clean air areas, The concentration in outdoor air increases accordingly in urban areas with industrial settlement. The highest concentration of PCBs is ingested through food. Because of their good fat solubility, PCBs can also be transferred to the infant with the mother’s milk. In humans, the storage reservoir is the fatty tissue. The diagnosis of chronic PCB intoxication is difficult. The ingested doses are usually ingested as mixed exposures and the suspected diagnosis can often only be made by taking a very detailed history with recording the handling of materials containing PCBs. Fatigue, tiredness, nervousness or susceptibility to infection are thereby no primary symptoms for an exclusive PCB intoxication.
- To the load of the interiors of a house belong beside PCP, PCB, asbestos, formaldehyde if necessary microbiologically produced hydrocarbons of mushrooms.
