Sickle Cell Disease (Sickle Cell Anemia): Or something else? Differential Diagnosis

Blood, blood-forming organs-immune system (D50-D90).

  • Anemias (anemia) of other etiology (cause), unspecified.
  • Thalassemia – autosomal recessive hereditary synthesis disorder of the alpha or beta chains of the protein portion (globin) in hemoglobin (hemoglobinopathy/diseases resulting from impaired formation of hemoglobin).
    • Α-Thalassemia (HbH disease, hydrops fetalis/generalized fluid accumulation); incidence: mostly in Southeast Asians.
    • Β-Thalassemia: most common monogenetic disorder worldwide; incidence: People from Mediterranean countries, Middle East, Afghanistan, India and Southeast Asia.

Cardiovascular system (I00-I99).

  • Vascular occlusion due to unspecified cause.

Medication

  • See “Cause” under medications