Side effects | Adumbran

Side effects

Taking adumbran for longer than one week carries a high risk of dependence. Due to the reduced quality of sleep, various side effects may occur, for example: especially a prolonged reaction time may affect the ability to drive and operate machines. However, these side effects can be alleviated by a sleep duration of at least seven hours.

Other side effects can include dizziness, which in combination with occasional muscle relaxation can result in movement insecurity. The relatively most frequently occurring side effects are listed, but there is no claim to completeness. More detailed information can be found in the package insert. – Light-headedness

  • Tiredness
  • Concentration disorders


Since adumbran itself already has an inhibitory effect on brain activity, the parallel intake of drugs that also have an activity-reducing effect is only possible with the prior consultation of a doctor and with caution. These medications include Furthermore, interactions with certain hypertension drugs as well as with drugs for the treatment of diabetes mellitus (diabetes) have been established. – psychotropic drugs,

  • Medicament for the treatment of epilepsy,
  • Strong analgesics (opiates) and some drugs against
  • Allergies (sedative antihistamines).

How does Adumbran work?

The activity level of the brain is influenced by messenger substances. There are those that increase the level of alertness and activity of the brain and those that weaken it. As a member of the benzodiazepine family, oxazephan enhances the action of the inhibitory neurotransmitter GABA in the brain and thus has an activity-suppressing effect.

The effect lasts eight to ten hours. Adumbran makes use of this calming or sleep-inducing effect of oxazephan. The disadvantage is that it makes it easier to fall asleep and sleep through the night, but the quality of sleep decreases.

However, with sufficient sleep, performance during the day is hardly affected. A far greater problem is the addictive potential of the adumbran. Already after one week of taking it, the body develops an addiction.

Withdrawal must take place gradually, as the symptoms temporarily reappear as a result of sudden withdrawal (reboud phenomenon). Adumbran is taken in tablet form and then absorbed through the gastrointestinal tract. The effect begins somewhat later than with other drugs in the same group.

The onset of action may be slightly different for each person. Usually the first effect is felt after about 30 minutes. The maximum effect is reached after about one to three hours. The total duration of effect of Adumbran is between eight and twelve hours.

Alternatives to Adumbran

As an alternative to adumbran, various medicines and plant substances are suitable. The extent of the symptoms should always be decided together with a doctor. In cases of moderate restlessness or mild sleep disorders, plant substances such as valerian or St. John’s wort have also been proven to have a good effect. For more severe symptoms, other drugs in the benzodiazepine group can be used as an alternative to adumbran. On the other hand, some antidepressants can be used, especially for anxiety disorders.