Side effects
Side effects on the eyes initially manifest themselves in blurred vision. Since Arcoxia® suppresses inflammatory processes of the body’s own immune system, which would be responsible for killing harmful pathogens, infections occur more frequently. This side effect on the eyes then usually takes the form of conjunctivitis and occurs in 1-0.1% of cases.
As a further side effect of taking Arcoxia®, fatigue can occur in 1-10% of applications. In many cases, fatigue is then accompanied by headache and dizziness. However, it can also be caused by the sleep disorders that occasionally occur when taking Arcoxia.
Tiredness is a common side effect of Arcoxia. A side effect classified as “common” (occurs in 1-10% of patients treated). Often there is also a feeling of weakness.
Flu-like symptoms can also occur. This may be due to an effect of Arcoxia on the central nervous system. However, this has not yet been conclusively investigated.
Caution is advised when taking Arcoxia® and alcohol at the same time. Arcoxia® inhibits the enzyme cyclooxygenase 2 (COX2). Like the enzyme COX1, which is only slightly different in structure, this enzyme is responsible for forming certain enzymes, the prostaglandins.
These enzymes are responsible for the proper structure of the stomach lining. By inhibiting the cyclooxygenases, the stomach lining is therefore no longer built up properly, leaving the stomach less protected and more vulnerable. Although COX1 is more abundant in the stomach, the effect of the inhibition of COX2 by Arcoxia is sufficient to influence the stomach lining.
If this is weakened, the stomach is more strongly attacked by the acid of the alcohol and nausea or even gastric bleeding can occur. For this reason especially the long intake of Arcoxia is not compatible with alcohol. The enzyme (COX2), which is inhibited by Arcoxia®, is found in the kidneys to a greater extent.
The kidney is responsible for regulating the body’s fluid volume and for lowering blood pressure by excreting water. Especially in cases of already limited kidney function, the prostaglandins produced by COX2 are very important for the blood circulation in the kidney and its function. Therefore, by taking Arcoxia® and inhibiting COX2, the kidney can further lose function and excrete less water.
As a side effect of Arcoxia®, blood pressure rises in 1-10% of applications. Furthermore, the effect of some antihypertensive drugs can be reduced by Arcoxia®. Among the side effects that can occur when taking Arcoxia® are Since every person reacts individually to medication, side effects can of course also occur which are not mentioned here.
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- Allergic reactions: skin rash (redness, itching) blood pressure drop shock
- Skin rash (redness, itching)
- Blood pressure drop
- Shock
- Gastrointestinal complaints gastritis gastric mucosa inflammation
- Gastritis
- Water retention in the tissue (edema)
- Tinitus
- Headaches
- Mental health problems: Drowsiness Lack of concentration Depression
- Drowsiness
- Lack of concentration
- Depression
- Laboratory changes (laboratory values) Increase of liver enzymes in the blood Decrease of red blood cells
- Increase of liver enzymes in the blood
- Erythropoiesis
- Cardiovascular problems Palpitations High blood pressure
- Palpitations
- High blood pressure
- Skin rash (redness, itching)
- Blood pressure drop
- Shock
- Gastritis
- Drowsiness
- Lack of concentration
- Depression
- Increase of liver enzymes in the blood
- Erythropoiesis
- Palpitations
- High blood pressure
Arcoxia® is mainly used to treat pain. If the medication with Arcoxia® is discontinued, the pain may reoccur. Many patients then perceive this pain more strongly.
Arcoxia® can usually be discontinued without reducing the dose. Most of the side-effects of the medication will disappear of their own accord when the medication is discontinued. Only the reduction of the increased body weight may take some time. How quickly you lose weight again depends on your eating habits and physical activity.
