Metformin is one of the best known drugs for the treatment of type 2 diabetes. Type 2 diabetes is an acquired diabetes, also known as “adult-onset diabetes”, which, according to a possible genetic predisposition, is aggravated by overweight and leads to permanently elevated blood sugar levels. In order to reduce the excessive sugar levels in the blood, the body itself has a very effective hormone, insulin.
Since the pancreas – also known as the pancreas – is no longer able to produce insulin when blood sugar levels are permanently elevated and stops working, the body can no longer lower insulin levels on its own after a certain point. The situation is further aggravated by the fact that over time the body cells no longer react to insulin, i.e. insulin resistance develops. The combination of these two factors leads to type 2 diabetes. Metformin helps to lower blood sugar levels. It is now considered the treatment of choice for diabetes mellitus and is used millions of times worldwide for the treatment of type 2 diabetes mellitus.
Mode of action
The exact mechanism of action of metformin is not yet 100% clear. On the one hand, metformin inhibits the new formation of sugar in the body itself. This takes place mainly in the liver.
On the other hand, it is being discussed whether metformin also inhibits the absorption of sugar in the intestine. This would mean that sugar absorbed with food would no longer reach the bloodstream via the intestinal wall. Whether metformin actually inhibits this process is, however, the subject of debate.
However, some bodybuilders use metformin to reduce the fat content of their bodies. If metformin actually inhibits the absorption of sugar in the intestine, less sugar is converted into less fat – and the body fat percentage drops. However, the undoubtedly helpful effects of metformin can be associated with various side effects and should only be taken if there is an actual indication, i.e. type 2 diabetes.
