Single Joint Pain (Monarthropathy): Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests.

  • Small blood count
  • Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
  • Urine status (rapid test for: nitrite, protein, hemoglobin, erythrocytes, leukocytes) incl. sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing of suitable antibiotics for sensitivity / resistance).
  • Uric acid

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Renal parameters – urea, creatinine (creatinine clearance if necessary).
  • Anti-citrulline antibodies – if rheumatoid arthritis is suspected.
  • Antinuclear antibodies (ANA) – when rheumatoid diseases are suspected.
  • Rheumatoid factor (RF)
  • Infectious serology – if previous infection is suspected: Chlamydia, Chlamydia pneumoniae, Mycoplasma pneumoniae, Yersinia, Salmonella.
  • Joint puncture with bacteriological, microscopic and chemical / immunological examination – on suspicion of bacterial arthritis, hemarthrosis (disease of a joint by repeated and persistent bleeding), gout (due toSynovia analysis).
  • Microbiological smears and/or cultures (aerobic and anaerobic blood cultures; 2 times 2 or better 3 times 2 blood cultures) – if septic arthritis is suspected.