Joint European League Against Rheumatism (EULAR) and American College of Rheumatology (ACR) classification criteria for primary Sjögren’s syndrome.
| Criterion | Points |
| Focal lymphocytic sialadenitis (salivary gland inflammation) with a focal score of ≥1 foci/4 mm². | 3 |
| Anti SS-A/Ro antibody positiveNote: Anti SS-A/Ro antibodies may also be present in systemic lupus erythematosus (SLE). | 3 |
| Ocular staining score ≥ 5 in at least one eye (alternatively, Van Bijsterveld score ≥ 4). | 1 |
| Schirmer test (measurement of tear production volume ) ≤ 5 mm/5 min in at least one eye. | 1 |
| Non-stimulated salivary flow rate ≤ 0.1 ml/min | 1 |
Interpretation: if the total sum is ≥ 4, the criteria for primary Sjögren’s syndrome are met.
Application of these criteria provides a specificity (probability that actually healthy individuals who do not have the disease in question will be detected as healthy by the test) of 95% and a sensitivity (percentage of diseased patients in whom the disease is detected by application of the procedure, i.e., a positive finding occurs) of 96%.
If any of the questions listed below are answered positively, the above criteria should be used to identify primary Sjögren’s syndrome.
- Have you had daily problems because your eyes were dry for a period of more than 3 months?
- Do you repeatedly have the feeling of sand or grit in your eye?
- Do you use tear substitute fluid more than three times a day?
- Have you had a dry mouth sensation daily for a period of at least 3 months?
- Do you drink frequently to be able to swallow dry food meals?
