Pathogenesis (disease development)
A skin abscess is an encapsulated collection of pus in the skin that results from an inflammatory tissue meltdown. They can occur with or without an external cause.
Furuncle refers to folliculitis (inflammation of a hair follicle) that melts centrally like an abscess.Furunculosis (synonym: furunculosis) is the repeated occurrence of numerous furuncles on different parts of the body. Deeper, follicular areas of the skin are affected. Furunculosis is often associated with metabolic disease (e.g., diabetes mellitus). Notice: In very rare cases, the causative agents are highly virulent strains of MRSA (people from farms?).
A carbuncle (boil) is a deep and usually very painful suppuration of several adjacent hair follicles or the confluence of several adjacent boils.
The above skin infections are usually caused by the bacterium Staphylococcus aureus.
Etiology (Causes)
Biographic causes
- Genetic burden from parents, grandparents (cellular immunodeficiency, e.g., leukopenia).
- Occupations – people from farms (think MRSA if furunculosis).
Behavioral causes
- Poor hygienic conditions
Disease-related causes
Blood, blood-forming organs – immune system (D50-D90).
- Iron deficiency anemia
- Impaired immune defenses, unspecified
Endocrine, nutritional and metabolic diseases (E00-E90).
- Diabetes mellitus (diabetes).
Skin and subcutaneous (L00-L99)
- Impetigo (impetigo)
- Sycosis – chronic inflammation of hair follicles.
Causes (external) of morbidity and mortality (V01-Y84).
- Atopic (hypersensitivity)
Other causes
- Operation
- I. m (intramuscular/”into a muscle”) injection (syringe) [→ syringe abscess].
- Foreign body
Laboratory diagnoses – laboratory parameters that are considered independent risk factors.
- Iron deficiency
