Laboratory parameters of the 1st order – obligatory laboratory tests.
- Small blood count
- Differential blood count
- Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
- Coagulation parameters – PTT, Quick
Laboratory parameters 2nd order – depending on the results of the history, physical examination and mandatory laboratory parameters – for differential diagnostic clarification.
- Electrolytes – calcium
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Plasma electrophoresis – if hypergammaglobulinemia, cryoglobulinemia, paraproteinemia is suspected.
- Rheumatism diagnostics – CRP (C-reactive protein) or BSG (blood sedimentation rate); rheumatoid factor (RF), CCP-AK (cyclic citrulline peptide antibodies), ANA (antinuclear antibodies).
- Skin biopsy (tissue removal from the skin) – if vasculitis (vascular inflammation) is suspected.
- Bone marrow biopsy – for suspected aplastic anemia (form of anemia (anemia) caused by pancytopenia (reduction of all cell rows in the blood; stem cell disease) and a concomitant hypoplasia).
Note: An increased bleeding tendency exists when the platelet count is below 150,000/μl. Spontaneous skin bleeding may occur at platelet counts of 30-20,000/μl and spontaneous hemorrhage at levels below 10,000/μl.
