Systemic Inflammatory Response Syndrome (SIRS): Or something else? Differential Diagnosis

Diseases that may cause SIRS:

Infectious and parasitic diseases (A00-B99).

  • Bleeding, unspecified
  • Ischemia, unspecified – reduced blood supply to an organ.

Liver, gallbladder and bile ducts – Pancreas (pancreas) (K70-K77; K80-K87).

Mouth, esophagus (esophagus), stomach, and intestines (K00-K67; K90-K93).

  • Ileus (intestinal obstruction)

Injuries, poisoning, and other consequences of external causes (S00-T98).

Diseases that can lead to sepsis:

Infectious and parasitic diseases (A00-B99).

  • Infections with pathogens of all types, especially bacteria such as Staphylococcus aureus or Escherichia coli.

Common forms of sepsis include the following.

  • Catheter/foreign body-associated sepsis – sepsis caused by catheters or other foreign bodies inserted into the body.
  • Ventilator-associated pneumonia – pneumonia associated with artificial ventilation.

Fulminant courses include.

  • Meningococcal sepsis – sepsis caused by Neisseria meningitidis.
  • OPSI syndrome (overwhelming post splenectomy infection syndrome) – sepsis after splenectomy (splenectomy).
  • Toxic shock syndrome (TSS, Engl. Toxic shock syndrome; synonym: tampon disease); severe circulatory and organ failure due to bacterial toxins (usually enterotoxin of the bacterium Staphylococcus aureus/superantigen effect of toxic-shock-syndrome toxin (TSST-1), more rarely streptococci, then called streptococcal-induced toxic shock syndrome); for the diagnosis of “TSS” three or more of the following organ systems must be involved: Gastrointestinal tract/gastrointestinal tract (vomiting, nausea, or diarrhea/diarrhea), musculature (marked myalgias/muscle pain with elevation of serum creatinine or phosphokinase), mucous membranes (vaginal, oropharyngeal, or conjunctival hyperemia)/increased accumulation of blood, kidneys (elevation of serum urea or creatinine, pyuria/excretion of pus in urine without evidence of urinary tract infection), liver (elevation of transaminases, bilirubin, or alkaline phosphatase), CNS (disorientation, impaired consciousness)