Tepoxaline

Products

Tepoxaline is commercially available in tablet form (Zubrin). It has been approved in many countries since 2003.

Structure and properties

Tepoxaline (C20H20ClN3O3, Mr = 385.8 g/mol) is a pyrazole derivative.

Effects

Tepoxaline (ATCvet QM01AE92) is analgesic and anti-inflammatory. The properties are based on inhibition of prostaglandin synthesis. The effects are mainly mediated by the active acid metabolite. Tepoxaline is a dual COX/5-LOX inhibitor.

Indications

Tepoxaline is used in dogs to treat inflammatory and painful musculoskeletal disorders.