Terpine Hydrate

Products

Terpine hydrate is commercially available in suppository form (Rectoseptal, combination). It has been approved in many countries since 1951.

Structure and properties

Terpine hydrate (C10H20O2 – H2O, Mr = 190.3 g/mol) exists as a white crystalline powder or as colorless and shiny crystals. It is sparingly soluble in water.

Effects

Terpine hydrate (ATC R05CA10) is believed to have expectorant, cough-irritant, anti-inflammatory, and antiseptic properties.

Indications

For supportive treatment of bronchial and pulmonary diseases.

Dosage

According to the SmPC. Suppositories are administered one to three times daily.

Contraindications

Terpin hydrate is contraindicated in hypersensitivity. For complete precautions, see the drug label.

Interactions

There are no known interactions with other drugs.

Adverse effects

Possible adverse effects include digestive discomfort. Use in infants is controversial and is not recommended by the EMA.