Testicular Swelling: Test and Diagnosis

2nd order laboratory parameters – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification

  • Small blood count
  • Inflammatory parameters – CRP (C-reactive protein).
  • Urine status (rapid test for: pH, leukocytes, nitrite, protein, blood), sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing suitable antibiotics for sensitivity / resistance).
  • Urethral swab (urethral swab) – if infection with e.g. chlamydia, gonorrhea (gonococci) is suspected.
  • Electrolytescalcium, chloride, potassium, magnesium, sodium, phosphate.
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
  • NT-proBNP (N-terminal pro brain natriuretic peptide) – for suspected heart failure (cardiac insufficiency).
  • Infectious serology or PCR diagnostics – for suspected leprosy, syphilis, tuberculosis.
  • Renal parameters – urea, creatinine.
  • AFP (alpha-fetoprotein), ß-HCG (human chorionic gonadotropin) – if testicular tumor is suspected* .
  • NSE (neuron-specific enolase) – sensitivity (percentage of diseased patients in whom the disease is detected by the use of the test, i.e. a positive test result occurs) of circa 60% for seminoma* .

* See laboratory diagnostics in testicular cancer (testicular cancer).