Pathogenesis (disease development)
The bacterium Clostridium tetani is ubiquitous in the soil, as well as in the intestines of humans and animals.
If contact with Clostridium tetani occurs via a wound, the bacterium enters the body and forms toxins (poisons) for the body. In particular, the toxin tetanospasmin is significant because it travels along nerve fibers to the spinal cord and brainstem and attacks the nerve cells that control muscles, causing the symptoms mentioned earlier.
Etiology (Causes)
Behavioral causes
- Contact of wounds with contaminated soil.
- Insufficient protection by vaccination
- Not hygienic care of the umbilical cord in the newborn.
Causes related to disease
- Chronic ulceration (ulcers) or abscesses.
- A connection of the development of tetanus with burns or frostbite can not be excluded
