The Therapy | Cushing’s disease

The Therapy

In Cushing’s disease, surgical removal of the pituitary gland tumor is usually performed. If a surgical intervention is not possible, there are other treatment measures that can be considered. These include proton radiation of the tumor tissue or the administration of certain drugs. The drug therapy includes cortisol lowering substances. These are intended to reduce the typical symptoms caused by hypercortisolism.

The prognosis

Cushing’s disease, which is caused by a tumor in the cerebral necrotic gland and can be treated surgically, usually has a normal life expectancy. If surgical removal is not possible, it is important to reduce the cortisol levels in the blood with medication. A permanently increased cortisol level has a negative effect on the cardiovascular system. In particular, elevated blood pressure can lead to complications such as a heart attack or stroke, which can significantly reduce the life expectancy of those affected.

Cushing’s disease in dogs

Cushing’s disease can also occur in dogs. As in humans, the most common trigger is a tumor in the pituitary gland, which is responsible for increased cortisone production. The animals show various symptoms, including weight gain, hair loss, increased urination, pronounced thirst behaviour, muscle weakness and thinning and more heavily pigmented skin.

Cushing’s disease in dogs is usually treated with drugs that reduce the production of cortisol. The drug therapy must be given for life so that the dog does not suffer from the typical symptoms of Cushing’s disease. With consistent treatment and regular blood checks at the veterinarian, a good therapy success can usually be expected.

Cushing’s disease in cats

Cats show almost the same symptoms as dogs in Cushing’s disease. These include hair and coat loss, an increase in body weight, muscle wasting, and increased thirst and hunger. Also a “thinning” skin and increased urination are among the possible symptoms.

Cats, however, in contrast to dogs, are often noticed by their owners only in very late stages or with already strongly pronounced symptoms. Often the animals therefore only come to the veterinarian when they are already very ill. Cats can also be treated with cortisol-reducing medication, but unlike dogs, the symptoms do not always regress. In general, no statement can be made about the prognosis for cats. The prognosis depends on the severity of the disease as well as on the remaining health condition of the cat.