Therapy
The main aim of the therapy of a gout attack is both the rapid relief of the pain symptoms and the inhibition of the spread of inflammatory processes in the area of the affected joints. The treatment of an acute attack of gout is generally carried out by the administration of various drugs. In particular, drugs that belong to the class of non-steroidal anti-inflammatory drugs (NSAIDs) are suitable for pain relief and inflammation inhibition.
Non-steroidal anti-inflammatory drugs inhibit an important enzyme (so-called cyclooxygenase), which is needed for the synthesis of various pain and inflammation mediators. The most commonly used drugs for the treatment of acute attacks of gout are Although indomethacin promises good efficacy in patients suffering from a gout attack, the drugs just mentioned are preferable due to the frequent side effects. Furthermore, Arcoxia® 90mg from the group of Coxibe can also be given in acute gout attacks.
Taking aspirin (acetylsalicylic acid) during a gout attack is not recommended, as this drug has an inhibitory effect on uric acid excretion. Many affected patients also respond very well to therapy with colchicine. Colchicine inhibits the uptake of urate crystals into the body’s macrophages via various mechanisms.
In this way, it also reduces the release of inflammatory mediators (cytokines) induced by the macrophages and thus has an anti-inflammatory effect. Colchicine is the poison of the autumn timeless, which has been used in medicine for many decades. When administering colchicine, however, it should be noted that it is a highly toxic poison and for this reason a low dosage must always be maintained.
In patients suffering from renal insufficiency, the poison of the Autumn Seasonless must not be used. In addition to the medicinal treatment of the gout attack, a targeted change in diet can also be useful. This measure reduces above all the probability of further disease events.
Patients who suffer from a gout attack should change to a diet low in purine in the future. The reduction of the purine (an organic base) ingested with the food ensures that less uric acid can be formed in the course of metabolism. In addition, a general diet should be aimed at reducing weight and avoiding overweight.
Abstaining from some specific foods can effectively help to prevent a further attack of gout.To the problematic food belong above all: The consumption of vegetable proteins is in contrast to it completely unproblematic. Also the consumption of alcoholic beverages should be strongly decimated around a further attack of gout to prevent. According to extensive studies, the best long-term treatment results can be achieved in those patients who undergo both drug therapy and extensive and efficient changes in their diet.
- Ibuprofen and
- Diclofenac
- Animal proteins
- Liver
- Herring
- Anchovies and
- Red meat
