Therapy of a purulent meningitis

Synonyms in a broader sense

Bacterial meningitis, hood meningitis, convexity meningitis, leptomeningitis, meningococcal meningitis, antibiotic Medical: Meningitis purulenta

Definition

The term purulent meningitis (purulent meninges) describes a purulent inflammation (-itis) of the meninges (meninges), which can be caused by various pathogens. The purulent meningitis (purulent meningitis) is usually caused by bacteria. It is accompanied by high fever and a severe general clinical picture such as clouding of consciousness and is an absolute emergency that must be treated immediately.

General Information

General information on the topic: “What is meningitis?” can be found under our topic:

  • Meningitis and
  • Purulent meningitis

Foreword

The therapy of purulent meningitis is usually carried out first, if the pathogen is not known, against the suspected most probable pathogen and is adjusted after microbiological detection of the bacterium (this takes a few days until the bacterium can be cultured and determined) and antibiogram (resistance testing of the germ against various antibiotics). The dosages mentioned are examples and can be treated differently in individual cases. In spite of all care taken, errors in dosage or other errors of content can occur in the medications mentioned below.

Therapy of purulent meningitis

Meningococcal therapy

Penicillin G (G=intravenous, i. v.) | 4x/day 6-10 Mega or Ampicillin | 3x/day 5 g i. v. or Cephalosporin (Ceftriaxon, Cefotaxim) | 3x/day 2 g i. v.

Pneumococcus therapy

Penicillin G (if sensitive): 4x/day 6-10 Mega or Cephalosporin (Ceftriaxon, Cefotaxim): 3x/day 2 g i. v. or Ampicillin: 3x/day 5 g i. v. Meropenem: 3x/day 2 g i. v.

Penicillin-resistant Pneumococcus

Cephalosporin plus vancomycin | 3x/day 2 g i. v. 2 g/day every 6 – 12 hours Cephalosporin plus rifampicin | 3x/day 2 g i. v.

Therapy Haemophilus influenzae

Cephalosporin (ceftriaxone, cefotaxime) | 3x/day 2 g i. v. alternatively ampicillin plus chloramphenicol | 3x/day 5 g i. v.

Therapy Listeria monocytogenes

Ampicillin plus gentamycin | 3x/day 5 g i. v. or trimethoprim-sulfamethoxazole | 1x/day 360 mg i. v. , max. 6 mg/kg or meropenem | 3x/day 2 g i. v. or cotrimoxazole | 2x/day 960 mg i. v.