Tolfenamic Acid

Products

Tolfenamic acid is commercially available as tablets and as a solution for injection as a veterinary drug. It has been approved in many countries since 1997.

Structure and properties

Tolfenamic acid (C14H12ClNO2, Mr = 261.7 g/mol) is an anthranilic acid derivative and therefore has a similar structure to mefenamic acid (Ponstan, generic). The aminobenzoic acid derivative exists as a white to pale yellow crystalline powder that is practically insoluble in water.

Effects

Tolfenamic acid (ATCvet QM01AG02) has anti-inflammatory, analgesic, and antipyretic properties. The effects are due to inhibition of prostaglandin synthesis.

Indications

For the treatment of pain and inflammation in dogs, cats, cattle, and pigs.