2nd order laboratory parameters – depending on the results of the medical history and physical examination – for differential diagnostic clarification.
- Small blood count
- Inflammatory parameters – CRP (C-reactive protein).
- Fasting glucose, if necessary oral glucose tolerance test (oGTT).
- Vitamin B6, B12, folic acid
- Iron, ferritin, transferrin
- Zinc
- Bacteriological and mycological cultures
- Tongue swab, tongue biopsy (tissue sampling from the tongue) if necessary.
- Detection of autoantibodies (IgG) against antigens in the cytoplasm of the salivary duct epithelium (biopsy material) (SS-A and SS-B (specific antibodies of ANA)) and autoantibodies against α-fodrin – in suspected Sjögren’s syndrome [SS-A pos.: 40-80%; SS-B pos.: 40-80%; ANA pos.: 70% of cases].
- AECA (anti-endothelial cell antibodies) – in suspected Kawasaki syndrome.