When the adrenal glands are disturbed, too much or too little hormone is produced – this results in over- or under-functioning of various organs with a variety of clinical pictures. Hyperfunction of the adrenal cortex When the adrenal cortex produces too much aldosterone, it leads to Conn’s disease (also known as hyperaldosteronism). Symptoms of Conn’s … Adrenal Cortex: Diseases
The adrenal cortex, as part of the adrenal gland, represents an important hormonal gland. Its hormones significantly control mineral metabolism, the body’s stress response, and sexual function. Diseases of the adrenal cortex can lead to severe hormonal dysfunction. What is the adrenal cortex? The adrenal cortex, together with the adrenal medulla, forms a paired hormonal … Adrenal Cortex: Structure, Function & Diseases
What is tertiary adrenal cortex insufficiency? In the literature, adrenal cortex hypofunction resulting from the inadequate intake or incorrect dose reduction of cortisol is often referred to as tertiary adrenal cortex insufficiency. In many cases, especially inflammatory diseases, cortisol can improve the symptoms. If cortisol is suddenly discontinued, the body’s lack of self-production can lead … Tertiary adrenal cortex insufficiency
Therapy The treatment of the tertiary form of adrenal cortex insufficiency is the same as for primary and secondary forms, with the administration of cortisol. The amount of cortisol should also be adjusted to the physical strain, i.e. the cortisol must be administered in higher doses in certain situations that put the body under stress. … Therapy | Tertiary adrenal cortex insufficiency
Difference to secondary adrenal cortex insufficiency Secondary adrenal insufficiency is a functional impairment of the pituitary gland or adenohypophysis. It is often a benign tumor that leads to such impairment. Without the effect of the hormones produced by the pituitary gland, the adrenal cortex lacks its drive to produce cortisol and the sex hormones (androgens). … Difference to secondary adrenal cortex insufficiency | Tertiary adrenal cortex insufficiency
Synonyms sex hormone, androgen, androstane, sex hormones Introduction Testosterone is a derivative of the sex hormone (androgen). Testosterone occurs in both sexes, but differs in concentration and effect. Tesotosterone is derived from testis (testicle) and steroid. The “inventor” of testosterone was Ernst Lageur, who was the first to extract bull testicles. In men, testosterone is … Testosterone
Side effects Among the most frequently observed side effects, especially in the form of overdose abuse are the following: Liver Diseases Kidney damage Cardiac arrhythmias Diseases of the cardiovascular system Arteriosclerosis Gynecomastia (butt formation in men) Steroid acne see: Acne Mental illnesses like depression Poorer memory performance Decrease in sperm count Reduction of the testicles … Side effects | Testosterone
Dexamethasone is an artificially produced active substance belonging to the group of glucocorticoids. In the human body, natural glucocorticoids (hormones) are produced in the adrenal cortex and fulfil a variety of regulatory tasks. The synthetic glucocorticoid dexamethasone has an inhibitory effect on inflammation and the immune system. Compared to the hormones produced in the adrenal … Dexamethasone
Price 10 tablets of dexamethasone with a dose of 8 mg per tablet cost just under 22 euros. However, dexamethasone is only available on prescription. If a cash prescription is submitted, 5 euros per prescription are charged. There are numerous different dosages (0.5 mg, 1.5 mg, 2 mg, 4 mg, 8 mg) and pack sizes. … Price | Dexamethasone
Dexamethasone inhibition test The so-called dexamethasone inhibition test is a provocation test. In a healthy organism, the production rate of the adrenal cortex and thus the concentration of glucocorticoids (e.g. cortisol) is controlled by a regulatory circuit between the pituitary gland and the adrenal cortex. At high cortisol concentrations, the production of a hormone of … Dexamethasone inhibition test | Dexamethasone
Interaction Dexamethasone can increase the excretion of potassium and thus enhance the effect of certain water tablets (diuretics). This can be dangerous if the potassium level drops too low, as this can lead to cardiac arrhythmia. Dexamethasone inhibits the blood sugar-lowering effect of drugs used to treat diabetes mellitus and blood thinners. Some antiepileptic drugs … Interaction | Dexamethasone
Introduction The drug Dermatop® is mainly sold as an ointment, cream or skin lotion, it contains the active ingredient prednicarbate. Prednicarbate belongs to the group of artificially produced glucocorticoids (steroid hormones) whose natural intermediates are formed in the adrenal cortex (e.g. cortisol). Dermatop® has strong anti-inflammatory, immunosuppressive, anti-pruritic and anti-allergic effects. It is generally used … Dermatop®
