Sympatholytics

Products Sympatholytics are commercially available in the form of tablets, capsules, as injectables, and eye drops, among others. Effects Sympatholytics have sympatholytic properties, meaning that they abolish the effects of the sympathetic nervous system, a portion of the autonomic nervous system. Their effects are usually due to direct antagonism at adrenoceptors. Indirect sympatholytics reduce the … Sympatholytics

Alfuzosin

Products Alfuzosin is commercially available in sustained-release tablet form and has been approved in many countries since 1994. In addition to the original Xatral, generic versions are also available. Structure and properties Alfuzosin (C19H27N5O4, Mr = 389.45 g/mol) is a quinazoline derivative. It is present in drugs as alfuzosin hydrochloride, a white crystalline powder that … Alfuzosin

Enantiomers

Introductory question How much active ingredient is in a 10 mg cetirizine tablet? (a) 5 mg B) 7.5 mg C) 10 mg The correct answer is a. Image and mirror image Many active pharmaceutical ingredients exist as racemates. They consist of two molecules that behave like an image and mirror image of each other. These … Enantiomers

Alfuzosin: Effects, Uses & Risks

Alfuzosin has been on the market for 30 years and is a proven treatment for prostatic hyperplasia. The alpha blocker relaxes the muscles of the prostate gland, leading to easier urination, and can be used in both mild and severe cases. What is alfuzosin? Alfuzosin relaxes the muscles of the prostate and urethra, urinary flow … Alfuzosin: Effects, Uses & Risks

Prostate Enlargement Causes and Treatment

Symptoms Benign hyperplasia of the prostate is a typical and chronic age-related condition in men. Approximately 50% of men over 50 and 80% of men over 80 are affected. The incidence and symptoms increase with age. Age is therefore the most important risk factor. The clinical symptoms are also called “benign prostatic syndrome”, because the … Prostate Enlargement Causes and Treatment

Tamsulosin

Products Tamsulosin is commercially available in the form of sustained-release tablets and sustained-release capsules and has been approved in many countries since 1996 (Pradif, Pradif T, generics). Tamsulosin is also available as a fixed combination with the 5alpha-reductase inhibitor dutasteride (Duodart), see under dutasteride tamsulosin. In 1996, sustained-release capsules were released (Pradif). Pradif T sustained-release … Tamsulosin

Hydrochloric Acid

Products Hydrochloric acid is available in various concentrations at specialty stores. Structure and properties Hydrochloric acid is the name given to an aqueous solution of hydrogen chloride gas (HCl). Concentrated hydrochloric acid exists as a clear, colorless liquid that fumes in air with a pungent odor and is miscible with water. It has a concentration … Hydrochloric Acid

Dutasteride, Tamsulosin

Products The 5alpha-reductase inhibitor dutasteride and the alpha-blocker tamsulosin are commercially available as a fixed combination in the form of capsules (Duodart, generics). The drug has been approved in many countries since 2010. Structure and properties Dutasteride (C27H30F6N2O2, Mr = 528.5 g/mol) is a 4-azasteroid and structurally closely related to finasteride. It exists as a … Dutasteride, Tamsulosin

Urinary Incontinence: Causes and Treatment

Symptoms Urinary incontinence manifests as involuntary leakage of urine. The common problem poses a psychosocial challenge for those affected, which can lead to changes in personal activities and a loss of quality of life. Risk factors include female gender, age, obesity, and numerous medical conditions. Causes Urinary incontinence can occur as a result of pathologic, … Urinary Incontinence: Causes and Treatment

Fosamprenavir: Effects, Uses & Risks

The active medical ingredient fosamprenavir is a so-called antiviral from the family of HIV protest inhibitors. It is used to treat HIV infections and is intended to prevent the development of AIDS (short for Acquired Immune Deficiency Syndrome). Fosamprenavir is marketed under the trade name Telzir and is manufactured by GlaxoSmithKline plc, based in London, … Fosamprenavir: Effects, Uses & Risks

Silodosin

Products Silodosin has been approved in hard capsule form in the United States since 2008, in the EU since 2010, and in many countries since 2016 (Urorec). Generic versions are registered in some countries. Structure and properties Silodosin (C25H32F3N3O4, Mr = 495.5) exists as a white to yellowish powder that is sparingly soluble in water. … Silodosin

Alpha Blocker

Products Alpha blockers are available in many countries in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. The most commonly prescribed today is tamsulosin (Pradif T, generic). Alpha blocker is short for alpha1-adrenoreceptor antagonist. Structure and properties The first alpha blockers-alfuzosin, doxazosin, and terazosin-were developed as derivatives of quinazoline: Effects Alpha blockers (ATC … Alpha Blocker