What prenatal diagnostics can – and cannot do “The main thing is healthy” has always been the main wish of all expectant parents. Modern prenatal diagnostics makes it possible to obtain information about the baby’s health development already in early pregnancy. From a medical point of view, prenatal diagnostics therefore serves to detect developmental disorders … Amiodarone: Effect, application, side effects
Paliperidone is an atypical neuroleptic. It has high neuroleptic potency. What is paliperidone? Paliperidone is classified in the group of atypical neuroleptics. It is used for schizophrenia. Paliperidone is categorized in the group of atypical neuroleptics. The drug is used in the EU under the preparation names Invega and Xepilon against schizophrenia. Paliperidone is the … Paliperidone: Effects, Uses & Risks
Products Digoxin is commercially available in many countries in tablet form and as a solution for injection and has been approved since 1960 (Digoxin Juvisé, original: Sandoz). Structure and properties Digoxin (C41H64O14, Mr = 780.96 g/mol) is a cardiac glycoside obtained from the leaves of . It is composed of three sugar units (hexoses) and … Digoxin: Drug Effects, Side Effects, Dosage and Uses
Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval
Indications For the treatment of cardiac arrhythmias. Active ingredients Class I (sodium channel blockers): class IA: Ajmaline (off-label). Quinidine (out of trade) Procainamide (out of commerce) Class IB: Lidocaine Phenytoin (not approved for this indication in many countries). Tocainide (not commercially available in many countries). Mexiletine (not on sale in many countries). Class IC: Encainid … Antiarrhythmics
Products Polysorbate 80 is present in many drugs as an excipient. These include tablets, injectables (e.g., amiodarone), biologics (therapeutic proteins, vaccines), and solutions. It is also used in personal care products and in foods. Structure and properties Polysorbate 80 is a mixture of partial esters of fatty acids, mainly oleic acid, with sorbitol and its … Polysorbate 80
Products Orlistat is available in many countries in the form of capsules and has been approved since 1998 (Xenical, 120 mg, Roche Pharmaceuticals). In 2009, it was also approved for self-medication after specialist consultation with healthcare professionals without a doctor’s prescription at half the dosage (Alli, 60 mg, GlaxoSmithKline). The generic Xenical drug Orlistat Sandoz … Orlistat: Drug Effects, Side Effects, Dosage and Uses
Products Dronedarone is commercially available in the form of film-coated tablets (Multaq). It was approved in 2009, first in the United States, then in Canada, in many countries, and in November throughout the European Union. Structure and properties Dronedarone (C31H44N2O5S, Mr = 556.76 g/mol) is a benzofuran derivative and an analog of the antiarrhythmic drug … Dronedarone
Background That grapefruit juice can cause drug-drug interactions was discovered by chance in a clinical trial in 1989 and confirmed in an experiment by the same research group in 1991 (Bailey et al, 1989, 1991). This showed that simultaneous ingestion of grapefruit juice with the calcium channel blocker felodipine significantly increases the bioavailability of felodipine. … Interactions with Grapefruit Juice
Symptoms Photosensitivity often manifests like sunburn in extensive skin redness, pain, a burning sensation, blistering, and hyperpigmentation after healing. Other possible skin reactions include eczema, itching, urticaria, telangiectasia, tingling, and edema. The nails may also be affected less frequently and may peel off in front (photoonycholysis). The symptoms are limited to the areas of the … Photosensitivity
Products Pure iodine is available in specialty stores. Potassium iodide is available as a drug in tablet form and as a dietary supplement, among other products. The name iodine is obsolete and should no longer be used. Iodine stands for the chemical element and iodide for the negatively charged anion that forms salts with cations. … Iodine Health Benefits
Digoxin, like digitoxin, is extracted from foxglove (Digitalis lanata or Digitalis purpurea), which is why both are classified as digitalis glycosides. Cardiac glycosides increase the beating power of the heart muscle while lowering the heart rate. What is digoxin? Digoxin is a substrate of the P-glycoprotein from the group of so-called cardioactive glycosides (also cardiac … Digoxin: Effects, Uses & Risks
