Angina Pectoris: Symptoms, Types

Brief overview Symptoms: pain behind the sternum, radiation to other areas possible, tightness and/or shortness of breath often with fear of death, unstable form: life-threatening, in women/older people/diabetes atypical symptoms such as dizziness, nausea Causes and risk factors: oxygen deficiency of the heart usually due to coronary artery disease, risk factors: smoking, high blood pressure, … Angina Pectoris: Symptoms, Types

Zolmitriptan

Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan

Cardiology: Treatment, Effects & Risks

Cardiology is a field of medicine that is particularly concerned with the study, treatment and cure of heart disease. It is therefore also referred to literally as the “study of the heart“. In order to work as a cardiologist, physicians in Germany must be able to provide evidence of special training. What is cardiology? Cardiology … Cardiology: Treatment, Effects & Risks

Dihydropyridine

Products Dihydropyridines are commercially available in many countries in the form of film-coated tablets, sustained-release tablets, capsules, and injectables. Nifedipine from Bayer (Adalat) was the first active ingredient from this group to enter the market in the mid-1970s. Today, amlodipine (Norvasc, generics) is most commonly prescribed. Structure and properties The name 1,4-dihydropyridines is derived from … Dihydropyridine

Bisoprolol Effects and Side Effects

Products Bisoprolol is commercially available in film-coated tablet form as a monopreparation (Concor, generic) and as a fixed combination with hydrochlorothiazide (Concor plus, generic). It has been approved in many countries since 1986. In 2016, a fixed combination with perindopril was approved (Cosyrel). Structure and properties Bisoprolol (C18H31NO4, Mr = 325.4 g/mol) is present in … Bisoprolol Effects and Side Effects

Hyde Syndrome: Causes, Symptoms & Treatment

Hyde syndrome describes acquired stenosis of the aortic valve associated with angiodysplasias of the gastrointestinal tract. Prominent are colon acendens (ascending colon) and caecums (appendix). They may present with gastrointestinal bleeding, leading to anemia (anemia). What is Hyde syndrome? This condition is named after its discoverer, US internist Edward C. Hyde, who first described this … Hyde Syndrome: Causes, Symptoms & Treatment

Hydralazine: Effects, Uses & Risks

Hydralazine is a drug that has a vasodilator effect. It is used to treat heart failure as well as hypertension during pregnancy. What is hydralazine? Hydralazine belongs to the group of vasodilators. These are vasodilating agents that are used to lower high blood pressure. In Europe, however, the related dihydralazine is more commonly used. The … Hydralazine: Effects, Uses & Risks

Simvastatin: Effects, Uses & Risks

Simvastatin is a classic statin and is used as a cholesterol-lowering agent. It was approved in 1990 and is used relatively frequently. What is simvastatin? Simvastatin, chemically (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl-2,2-dimethylbutanoate, is a drug used primarily as a cholesterol-lowering agent. Simvastatin is structurally derived from the naturally occurring monacolin K, also known as lovastatin. Simvastatin is partially synthetically … Simvastatin: Effects, Uses & Risks