Immunology

Immunology deals with the body’s defense mechanisms and their disorders. The immune system is the bulwark against invading harmful bacteria, viruses, fungi, parasites and toxins. If the immune defense is weakened, such invaders have an easy time. However, an excessive immune reaction, such as occurs in allergies and autoimmune diseases, is also problematic. The tasks … Immunology

Short Feedback Mechanism: Function, Tasks, Role & Diseases

The term short-feedback mechanism originates from endocrinology. It refers to a regulatory circuit in which a hormone can directly inhibit its own action. What is the short-feedback mechanism? Short-feedback mechanisms are independent, very small control circuits. One example is the short-feedback mechanism of thyroid-stimulating hormone (TSH). The short-feedback mechanism is one of the regulatory circuits. … Short Feedback Mechanism: Function, Tasks, Role & Diseases

Basiliximab: Effects, Uses & Risks

Basiliximab is a drug in the immunosuppressant drug class. It is used to prevent rejection after liver or kidney transplantation. What is basiliximab? Basiliximab is a drug in the immunosuppressant drug class. It is used to prevent rejection after liver or kidney transplantation. Basiliximab is a drug substance that belongs to the group of chimeric … Basiliximab: Effects, Uses & Risks

Paracrine Secretion: Function, Role & Diseases

Paracrine secretion is the medical term for hormone secretion into the interstitium that acts on cells in the immediate environment. Paracrine secretion primarily serves to differentiate tissues. Paracrine disorders can affect bone formation, for example, and show effects on the entire hormonal system. What is paracrine secretion? Paracrine secretion is the medical term for hormone … Paracrine Secretion: Function, Role & Diseases

Felty Syndrome: Causes, Symptoms & Treatment

Felty syndrome is a disease of the rheumatic type. The inflammatory rheumatic disease is considered a special form of the so-called rheumatoid arthritis. In 1924, Felty syndrome was described for the first time. What is Felty syndrome Infographic of pain regions and affected joints in rheumatoid arthritis. Click image to enlarge. Felty syndrome affects women … Felty Syndrome: Causes, Symptoms & Treatment

Erenumab

Products Erenumab was approved in many countries, in the EU, and in the United States in 2018 as a solution for injection in a prefilled pen and a prefilled syringe (Aimovig, Novartis / Amgen). Structure and properties Erenumab is a human IgG2 monoclonal antibody directed against the CGRP receptor. It has a molecular weight of … Erenumab

Bickerstaff Encephalitis: Causes, Symptoms & Treatment

Bickerstaff encephalitis is a disease associated with inflammation in the brainstem. In addition, the nerves of the brain are affected by Bickerstaff encephalitis, so patients usually suffer severe disorders of consciousness. Recently, the medical community has been increasingly investigating the link between Bickerstaff encephalitis and Miller-Fisher syndrome. What is Bickerstaff encephalitis? Bickerstaff encephalitis was first … Bickerstaff Encephalitis: Causes, Symptoms & Treatment

Sputnik V

Products Sputnik V is a Covid-19 vaccine developed in Russia and the first vaccine from this group to be registered on August 11, 2020 (Gamaleya National Center of Epidemiology and Microbiology). The name is derived from the Sputnik satellite, which was the first satellite placed in Earth orbit by the Soviet Union in 1957. Sputnik … Sputnik V

Evolocumab

Products Evolocumab was approved in the EU and US in 2015 and in many countries in 2016 in the form of a solution for injection (Repatha). Structure and properties Evolocumab is a human IgG2 monoclonal antibody with a molecular mass of 141.8 kDa. It is produced by biotechnological methods. Effects Evolocumab (ATC C10AX13) has lipid-lowering … Evolocumab