Citalopram: Effects, Administration, Side Effects

How citalopram works Citalopram interferes with brain metabolism, more specifically with the metabolism of the nerve messenger (neurotransmitter) serotonin. Neurotransmitters transmit nerve signals between brain cells by being secreted by one cell and then binding to specific docking sites (receptors) on the next cell. The neurotransmitters are then reabsorbed into the cell of origin and … Citalopram: Effects, Administration, Side Effects

Amitriptyline: Effects, Usage, Side Effects

How amitriptyline works Amitriptyline is a drug from the group of so-called tricyclic antidepressants. It has a mood-lifting, anxiolytic and calming effect. Amitriptyline also alleviates the intensity of pain caused by nerve pain (neuropathic pain) and reduces the frequency of chronic tension headaches and migraines. Amitriptyline exerts these effects by influencing the sensitive balance of … Amitriptyline: Effects, Usage, Side Effects

Quetiapine

Products Quetiapine is commercially available in the form of film-coated tablets and sustained-release tablets (Seroquel / XR, generic, auto-generic). It has been approved in many countries since 1999. Generics of film-coated tablets entered the market in 2012, and generics of sustained-release tablets were first registered in 2013. Structure and properties Quetiapine (C21H25N3O2S, Mr = 383.5 … Quetiapine

Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Sulpiride (Dogmatil): Drug Effects, Side Effects, Dosage and Uses

Products Sulpiride is commercially available in the form of capsules and tablets (Dogmatil). It has been approved in many countries since 1976. Structure and properties Sulpiride (C15H23N3O4S, Mr = 341.4 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. It belongs to the substituted benzamides. Effects Sulpiride … Sulpiride (Dogmatil): Drug Effects, Side Effects, Dosage and Uses

Paroxetine

Products Paroxetine is commercially available as film-coated tablets and as a suspension (Deroxat, generic). It has been approved in many countries since 1993. Paroxetine is also marketed as Seroxat and Paxil in some countries. Slow-release paroxetine (CR) is not currently available in many countries. Structure and properties Paroxetine (C19H20FNO3, Mr = 329.4 g/mol) is present … Paroxetine

Melatonin Receptor Agonists

Products Melatonin receptor agonists are commercially available in tablet and capsule form. Structure and properties Melatonin receptor agonists are structurally derived from and related to the natural hormone melatonin. Effects Melatonin, a sleep hormone produced by the pineal (pineal) gland of the brain from tryptophan, has a central role in the body in regulating the … Melatonin Receptor Agonists

Melitracene

Products Melitracene is marketed in the form of film-coated tablets exclusively in combination with flupentixol (Deanxit). It has been approved in many countries since 1973. see under melitracene and flupentixol Structure and properties Melitracene (C21H25N, Mr = 291.4 g/mol) Effects Melitracene (ATC N06CA02) has antidepressant properties. Indications In combination with flupentixol: Mild to moderate states … Melitracene

Melitracene and Flupentixol

Products The fixed combination Deanxit with the two active ingredients melitracene and flupentixol is commercially available in many countries in the form of film-coated tablets. The drug has been approved since 1973, initially as dragées. The marketing authorization holder is the Danish company Lundbeck. Structure and properties The active ingredients are present in the drug … Melitracene and Flupentixol

Anthranoid

Definition Plant antraceene derivatives with the common structural feature 1,8-dihydroxyanthrone. Numerous derivatives (anthrones, anthranols, anthraquinones, dianthrones, naphthodianthrones). 1,8-Dihydroxyanthrone: Effects Laxative (Prodrugs) Antidepressant: St. John’s wort Antiarthrotic: Rhine, Diacerein (Verbonil). Cytotoxic: mitoxantrone (Novantrone). Indications Primarily for short-term treatment of constipation. Bowel emptying Some: Osteoarthritis Medicinal drugs Aloe: e.g. aloin A American rotten tree (Cascara bark) Sloth … Anthranoid