How Loratadine works Loratadine blocks the effects of the neurotransmitter histamine and thus relieves the symptoms of an allergic reaction: If histamine subsequently binds to its docking site (receptor), the typical symptoms of an allergy occur, such as increased blood flow to the tissue (redness, swelling, wheals), itching, watery eyes, runny nose, and even cramping … Loratadine: Effects, Applications, Side Effects
Products Medicines containing zipeprol are no longer on the market in many countries. Mirsol is no longer available. Zipeprol is classified as a narcotic. Structure and properties Zipeprol (C23H32N2O3, Mr = 384.5 g/mol) is a disubstituted piperazine derivative with a non-opioid structure. Effects Zipeprol (ATC R05DB15) has antitussive properties. In addition, anticholinergic, antihistamine, local anesthetic, … Zipeprol
Products Azelastine is available as a nasal spray and in eye drop form (eg, Allergodil, Dymista + fluticasone, generics). It has been approved in many countries since 1994. Structure and properties Azelastine (C22H24ClN3O, Mr = 381.9 g/mol) is present in drugs as azelastine hydrochloride, a white to almost white crystalline powder. It is a phthalazinone … Azelastine
After a bee sting, the skin swells badly and turns red, and a little later you experience shortness of breath and dizziness. No, this reaction is not normal. A life-threatening bee venom allergy is present. What is bee venom allergy? Bee venom allergy is a type of allergy. An allergy manifests itself in an overreaction … Bee Venom Allergy: Causes, Symptoms & Treatment
Terfenadine is an anti-allergic drug and is used to treat allergic reactions. Because it competes for the receptor site for histamine in the human body, the body’s own hormone histamine can no longer dock. Histamine is responsible for allergic symptoms such as itching and redness. Terfenadine is administered in tablet form. It has been withdrawn … Terfenadine: Effects, Uses & Risks
Withdrawal from the market Rhinathiol Promethazine (Sanofi-Aventis Suisse SA, category C) contained a combination of the sedative antihistamine promethazine and the expectorant mucolytic carbocisteine. According to the package insert, the syrup could be taken for both productive cough and irritable cough (1). It was frequently used in children. The drug was withdrawn from the market … Rhinathiol Promethazine
When allergens enter the body through the mucous membranes, they can lead to the release of large amounts of histamine as well as signaling substances such as cytokines and pro-inflammatory leukotrienes in a hypersensitive immune system. In the early stages of an allergic reaction, histamine in particular causes symptoms such as itching, sneezing attacks, fluid … Antihistamines: Uses and Side Effects
Product Cyclizine has been discontinued in many countries since 2008. Marzine is no longer available. Possible alternatives include the antihistamines dimenhydrinate or meclozine. Structure and properties Cyclizine (C18H22N2, Mr = 266.38 g/mol) is a piperazine derivative. In the drug, it is present as cyclizine hydrochloride. Effects Cyclizine (ATC R06AE03) has antihistamine, antiemetic, antivertiginous, and sedative … Cyclizine
Products Antazoline is fixed combination with tetryzoline in the form of eye drops commercially available (Spersallerg, Spersallerg SDU). It has been approved in many countries since 1967. Structure and properties Antazoline (C17H19N3, Mr = 265.35 g/mol) is present in drugs as antazoline hydrochloride, a white crystalline powder that is sparingly soluble in water. It is … Antazoline: Antihistamine
Products In many countries, drugs containing promethazine are currently no longer on the market. The last product to be withdrawn from the market was Rhinathiol promethazine with the expectorant carbocisteine on January 31, 2009. However, medicines are still available in many countries. The original drug is Phenergan. Promethazine was developed in the 1940s at Rhône-Poulenc, … Promethazine
Products There are currently no drugs containing carbinoxamine on the market in many countries. The active ingredient was previously contained in Rhinotussal capsules and Rhinotussal juice, among other products. Structure and properties Carbinoxamine (C16H19ClN2O, Mr = 290.8 g/mol) is present in drugs as carbinoxamine maleate, a white crystalline powder that is readily soluble in water. … Carbinoxamine
Symptoms Three different main courses can be distinguished: 1. A mild, local reaction manifests as burning, pain, itching, redness of the skin, and formation of a large wheal. The symptoms improve within 4-6 hours. 2. in a moderately severe course, there is a more severe local reaction, with symptoms such as reddening of the skin … Insect Bites
