Brief overview What is aortic coarctation? Congenital narrowing of the main artery (aorta) Course of the disease and prognosis: After successful treatment of the malformation, the prognosis is very good. Causes: Maldevelopment of the aorta in the first weeks of embryonic development Risk factors: In some cases, aortic isthmus stenosis occurs in families. Sometimes in … Aortic isthmus stenosis: Symptoms, Progression
Desmosine is a proteinogenic amino acid. Together with other amino acids, it forms the fiber and structural protein elastin. In mutations in the ELN gene, the structural formation of elastin is impaired. What is desmosine? Amino acids are an important component of the human organism. They are a class of organic compounds formed from at … Desmosine: Function & Diseases
The aortic valve is one of four heart valves or one of two so-called leaflet valves. It is located at the exit of the left ventricle into the aorta. The aortic valve opens during systolic contraction of the left ventricle and allows ejection of blood from the ventricle into the aorta, the beginning of the … Aortic Valve: Structure, Function & Diseases
Hypertrophic cardiomyopathy is an inherited heart muscle disease. Medical science distinguishes between an obstructive and a non-obstructive form. Patients with the nonobstructive form are often asymptomatic for a long time or even for life. What is hypertrophic cardiomyopathy? The group of cardiomyopathies summarizes diseases of the heart muscle. Cardiomyopathies are associated with mechanical or electrical … Hypertrophic Cardiomyopathy: Causes, Symptoms & Treatment
Introduction Aortic valve stenosis is a narrowing of the heart valve, which lies between the left ventricle of the aorta, the aortic valve. It is the most common heart valve defect in Germany. One consequence of the disease is usually an overload of the left heart, which initially leads to an enlargement of the heart … Aortic valve stenosis
Therapy The therapy of aortic valve stenosis depends on the severity of the disease, the symptoms that occur as well as any concomitant diseases and the patient’s general condition. While in mild to moderate aortic valve stenosis without symptoms there is controversial discussion as to whether surgical replacement of the aortic valve is justified, surgical … Therapy | Aortic valve stenosis
What are the life expectancies with aortic valve stenosis? Aortic valve stenosis is often a chance finding, since the heart adapts and even in severe cases it is possible that no or only minor symptoms occur. It is possible that over the years the valve narrowing will increase only very slightly or not at all. … What are the life expectancies with aortic valve stenosis? | Aortic valve stenosis
Forecast Since the symptoms of aortic valve stenosis often appear very late, the prognosis of the disease is relatively poor without surgical replacement of the valve, since the disease is already well advanced at the time of diagnosis. The individual prognosis is significantly influenced by the severity of the stenosis, but also by the general … Forecast | Aortic valve stenosis
In aortic stenosis, the junction between the heart and aorta is narrowed due to heart valve damage. The heart must exert more force to pump blood through the narrowing and will be damaged in the long term without therapy. What is aortic stenosis? Aortic stenosis is a heart valve defect that causes the outflow tract … Aortic Stenosis: Causes, Symptoms & Treatment
Elastin is a structural protein involved in building the connective tissue of the lungs, blood vessels, and skin. It is very elastic, unlike collagen, which is also found in connective tissue. Elastin molecules cross-link with each other in the extracellular space. What is elastin? All vertebrates contain the fibrous protein elastin. It is a structural … Elastin: Function & Diseases
What is aortic stenosis? Aortic stenosis is the short form of aortic valve stenosis and describes a congenital or acquired heart valve disease. In aortic stenosis, the aortic valve, the valve between the left ventricle and the aorta, is pathologically narrower than in healthy individuals. Typical is a progressive calcification of the valve pockets of … Aortic Stenosis
The classification Aortic valve stenoses are first classified according to their origin, i.e. acquired or congenital (inherited). In inherited aortic stenosis, the localization of the narrowing at the aortic valve must be distinguished: valvular/supravalvular/subvalvular aortic stenosis. The shape of the aortic valve can be unicuspid or bicuspid and refers to the presence of certain heart … The classification | Aortic Stenosis
