Cromoglicic Acid in Asthma

Products Cromoglicic acid had been approved for asthma therapy in many countries since 1969. After the original Lomudal, the generic Cromosol UD also went off the market in 2016. Medicines for inhalation are still available in Germany. Structure and properties The drugs contain sodium cromoglicate (C23H14Na2O11, Mr = 512.3 g/mol), a white, crystalline, hygroscopic powder … Cromoglicic Acid in Asthma

LABA

Products LABA is an acronym for , which means long-acting beta agonists (sympathomimetics). LABAs are mainly marketed as inhaled preparations (powders, solutions) administered with an inhaler such as a metered-dose inhaler, diskus, respimat, breezhaler, or ellipta. Some may also be given perorally. Salmeterol and formoterol were the first agents from this group to be approved … LABA

Mometasone

Products Mometasone furoate is commercially available as a cream, ointment, emulsion, and solution (Elocom, Monovo, Ovixan). It has been approved in many countries since 1989. This article refers to use on the skin. Nasal sprays are also available; see mometasone nasal spray. In 2020, a fixed combination with indacaterol was approved for asthma therapy (Atectura … Mometasone

Cortisone therapy for asthma

Introduction Glucocorticoids (cortisone) are, along with beta-2 sympathomimetics, the most important group of drugs in the treatment of chronic inflammatory lung diseases such as bronchial asthma or COPD (chronic obstructive pulmonary disease). Used as a respiratory spray or powder, they enter the lungs and bronchi directly. There, glucocorticoids control the development of inflammation of the … Cortisone therapy for asthma

Cortisone shock therapy | Cortisone therapy for asthma

Cortisone shock therapy In cortisone shock therapy, very high doses of cortisone are applied for a short period of time in the acute phase of a disease in order to achieve rapid relief of symptoms. The cortisone dose is then reduced relatively quickly to a dose that corresponds approximately to the Cushing’s threshold. Such a … Cortisone shock therapy | Cortisone therapy for asthma

What’s the Cushing’s threshold? | Cortisone therapy for asthma

What’s the Cushing’s threshold? The Cushing’s threshold is understood to be the maximum dose of cortisone preparations that can still be taken daily without the risk of developing a so-called Cushing’s syndrome. If high-dose therapy with cortisone preparations is continued over a longer period of time, there is a risk that the oversupply of cortisol … What’s the Cushing’s threshold? | Cortisone therapy for asthma

What are the alternatives to cortisone? | Cortisone therapy for asthma

What are the alternatives to cortisone? The cortisone preparations most frequently used in asthma therapy are budesenoside and beclomethasone. In addition to these cortisone preparations, beta-2 sympathomimetics play a particularly important role in asthma therapy. However, they differ significantly in their effect from the cortisone preparations mentioned. While the inhaled cortisosteroids have a long-term anti-inflammatory … What are the alternatives to cortisone? | Cortisone therapy for asthma

Indacaterol

Products Indacaterol is commercially available as hard capsules with a powder for inhalation (Onbrez Breezhaler) and has been approved since 2010. It is also combined fixed with the LAMA glycopyrronium bromide (Ultibro Breezhaler, approved 2014). The fixed combination with mometasone furoate (Atectura Breezhaler) was registered for asthma therapy in 2020. Finally, a combination of indacaterol … Indacaterol

Which asthma medicines contain cortisone? | Medicines for bronchial asthma

Which asthma medicines contain cortisone? Many medications used to treat asthma contain cortisone. The standard preparation for long-term asthma control is glucocorticoids, which usually contain cortisone or agents similar to cortisone. Glucocorticoids used in asthma are beclometasone, budesonide and fluticasone. However, these are usually very effective. Alternatively, leukotriene receptor antagonists (LTRA) can be used for … Which asthma medicines contain cortisone? | Medicines for bronchial asthma